Amsterdam institute for Immunology and Infectious Diseases

Christoph Bock is a Professor of (Bio)Medical Informatics at the Medical University of Vienna and works as a Principal Investigator at the Center of Molecular Medicine (CeMM) in Vienna.
His research combines experimental biology (high-throughput sequencing, epigenetics, CRISPR screening, synthetic biology) with computational methods (bioinformatics, machine learning, artificial intelligence) for cancer, immunology, and precision medicine. His lab studies the role of the epigenome in cancer, which provides a new perspective for understanding how cancer develops and how it can be diagnosed and treated. His approach is to combine both wet-lab and computational methods in order to explore opportunities for epigenetic combination therapies against cancer.
His lab uses the hematopoietic system and the development of leukemia as a model for dissecting the interplay of genetic, epigenetic and transcriptional mechanisms in the course of cellular differentiation and in leukemia. Furthermore, his lab has established an epigenetic biomarker platform for systematically deriving, prioritizing and validating DNA methylation biomarkers in cancer.