Amsterdam Gastroenterology Endocrinology Metabolism
Research highlights
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Artificial bihormonal pancreas in patients after total pancreatectomy (APPEL 5+)
Inreda Diabetic BV developed the first artificial bihormonal pancreas (AP) to improve treatment of diabetes by automatically controlling glucose concentrations.
Amsterdam Gastroenterology Endocrinology MetabolismOngoing
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Towards individual prognostication in Classical Galactosemia
Classical Galactosemia (CG) is an inborn error of galactose metabolism. In spite of early diagnosis and dietary treatment many patients develop neurological and cognitive complications.
Amsterdam Gastroenterology Endocrinology MetabolismCompleted
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Nationwide implementation study of an evidence-based management algorithm for patients with chronic pancreatitis (COMBO trial)
Current care in Dutch chronic pancreatitis proved not to be in accordance with the European Guidelines which may indicate suboptimal care.
Amsterdam Gastroenterology Endocrinology MetabolismOngoing
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Fatigue in Inflammatory Bowel Disease
Fatigue is a highly prevalent problem in inflammatory disease patients. Not only in active disease, but also in patients in remission.
Amsterdam Gastroenterology Endocrinology MetabolismOngoing
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Clinical, diagnostic and genetic aspects of congenital central hypothyroidism (CCeH)
The Dutch neonatal screening program allows for the detection of congenital central hypothyroidism (CCeH) and facilitated identification of patients with CCeH over the past decades.
Amsterdam Gastroenterology Endocrinology MetabolismCompleted
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From disease transcriptome to drug discovery
Researchers at the Laboratory Genetic Metabolic Disease are looking at drug development in a different way. Their computational pipelines are greatly accelerating the drug discovery process.
Amsterdam Gastroenterology Endocrinology MetabolismOngoing
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Gluten-related Neurological Disorders
Various neurodegenerative disorders have been associated with an inappropriate reaction to dietary gluten intake. The underlying neuropathological mechanism is still unclear.
Amsterdam Gastroenterology Endocrinology MetabolismOngoing
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Clinical and translational research in patients with polyposis syndromes
One of our main goals in clinical research in patients with polyposis syndromes is the optimization and personalization of endoscopic surveillance.
Amsterdam Gastroenterology Endocrinology MetabolismOngoing
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Targeting hepatic bile salt uptake to treat cholestasis or the metabolic syndrome
In this project we aim to understand the role of bile acids (and its dynamics) in energy, fat and glucose homeostasis, and in inflammation.
Amsterdam Gastroenterology Endocrinology MetabolismOngoing