PI
Specialization

Pathology/neuro-oncological pathology

Focus of research
  • Unraveling the molecular underpinnings of primary tumors of the central nervous system (CNS);
  • Translation of these findings in improved clinical diagnosis and classification of CNS tumors;
  • Elucidation of the role of the tumor microenvironment in the pathobiology and clinical behavior of CNS tumors.

Pieter Wesseling is a (neuro)pathologist and full professor at the department of Pathology at the Amsterdam UMC, and he is additionally affiliated with the Princess Máxima Center for Pediatric Oncology in Utrecht. Wesseling was trained as clinical (neuro)pathologist in the Radboud University Medical Center in Nijmegen (supervised by Prof. Joop L. Slooff), and in Duke University Medical Center in Durham NC, USA (Prof. Peter C. Burger. He has led multiple (inter)national research projects, (co-)authored more than 300 papers in international, peer-reviewed journals on neuro-oncological topics, is member of the editorial board of several international neuro-oncological and neuropathological journals. He is at present chair of the consortium to Improve Molecular and Practical Approaches for CNS tumor Taxonomy (cIMPACT-NOW) Steering Committee, was centrally involved in shaping the revised 4th edition of the WHO CNS tumor classification (2016) and is an expert editor of the 5th (2021) edition of this classification as well as of the WHO classification of Pediatric Tumors (2022).

Activities

  • Expert member of the editorial board of the WHO 2021 Classification of CNS tumors
  • Chair of the consortium to Improve Molecular and Practical Approaches to CNS Tumor Taxonomy/cIMPACT-NOW (link)
  • Chair of the International Collaboration of Cancer Reporting (Neuropathology branch)