Amsterdam institute for Immunology and Infectious Diseases

Lecture:

Immunity evolved in multicellular organisms to limit the negative impact from exposure to microbes. The immune system has the capacity to sense and target pathogenic microorganisms for containment, destruction or expulsion to preserve organismal homeostasis and fitness.

Multicellular organisms also evolved another defense strategy that preserves organismal homeostasis and fitness without directly impacting on microorganisms. This defense strategy, referred to as disease tolerance, relies on evolutionarily conserved stress and damage responses that limit the metabolic dysfunction and damage imposed on parenchymal tissues, either directly by pathogenic microorganisms or indirectly by immune-driven resistance mechanisms.

Understanding the cellular and molecular mechanisms governing this network of interactions may transform our understanding of host-microbe interactions and will impact on the treatment of infectious diseases.

Lecture by: Miguel Soares, Principal investigator at the Instituto Gulbenkian de Ciencia, Lisbon, Portugal.

Host: Derk Amsen

Masterclass:

Masterclass:

In his master class, Dr. Soares will give some insight into the development of important stories that have come from his lab, hurdles he had to overcome, the role of serendipity, In this, he will address topics like: “how do you identify an important question to work on?”, “how do you find the balance between doing very exciting but risky work and doing safe but less exciting work?” ; “how do you make sure that you can get your work funded?”; “how do you sell your work”; “how do you plan your career?”, etc.

Time and location Lecture: 1.00 at Sanquin auditorium and online
Time and location Masterclass: 2.30 – 4.30 pm at Sanquin at room B-108.