MRI, pathology, neurodegeneration

Focus of research

My main research aim is to translate post mortem MRI signatures of neuropathology and neurodegeneration to the clinical setting in order to facilitate a better interpretation of MRI datasets, contributing to a better diagnosis, prognosis and patient stratification. 

For this, we set up a standardized pipeline including Alzheimer’s disease and other dementia, Parkinson’s disease, and non-neurological control donors, all undergoing the same 3T in-situ MRI and autopsy protocol with subsequent pathological assessment.

With this approach, my research line is threefold: studying the influence of pathological and neuronal markers on (i) cortical alterations, (ii) specific nuclei and their projections, and (ii) the integrating and segregating brain network.