Amsterdam institute for Infection and Immunity
Research highlights
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ARCAID - Amsterdam Rheumatology Center for AutoImmune Diseases
ARCAID allows us to bring together 20 of the most talented young researchers in biomedicine from all over the world with top translational scientists.
Amsterdam institute for Infection and ImmunityOngoing
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Germline biomarkers of melanoma immunotherapy: an international consortium
Biomarkers that predict immunotherapy treatment success or risk of toxicity are urgently needed, to increase clinical benefit of metastatic melanoma patients.
Amsterdam institute for Infection and ImmunityOngoing
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IMI ImmuneImage
The objective of Immune-Image is to develop a novel non-invasive imaging strategy for assessing immune cell activation and dynamics.
Amsterdam institute for Infection and ImmunityOngoing
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Lyme borreliosis: diagnosis and management
Chronic symptoms attributed to Lyme borreliosis can be challenging to diagnose and treat. This state of the art and systematic review in the BMJ by Kullberg and collaborators offers a roadmap for physicians how to provide the best possible and personalised care for their patients.
Amsterdam institute for Infection and ImmunityOngoing
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Pharmacokinetic and pharmacodynamic target attainment of antibiotics in different patient populations
The adequacy of currently used dosing regimens of ciprofloxacin and ceftazidime are explored and if required improved.
Amsterdam institute for Infection and ImmunityOngoing
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Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability
Isolation of 403 monoclonal antibodies from COVID-19 patients revealed convergent gene usage and multiple target epitopes
Amsterdam institute for Infection and ImmunityOngoing
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Resident immune cells in lesion formation in advanced MS
MS is characterized by inflammatory attacks of infiltrating leukocytes at onset but evolves into a progressive disease within the central nervous system.
Amsterdam institute for Infection and ImmunityOngoing
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Selective tumor antigen vaccine delivery to human CD169+ antigen presenting cells using ganglioside-liposomes
Current immunotherapies only benefit a minority of cancer patients. We need new approaches to boost patients’ anti-tumor immune responses.
Amsterdam institute for Infection and ImmunityOngoing
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Single domain antibody targeting of the CD1d monomorphic antigen-presenting molecule induces potent anti-tumour activity
Camelid-derived single domain antibodies (VHH)5 specific for the human MHC class I-like molecule CD1d can modulate the function of CD1d-restricted T cell populations.
Amsterdam institute for Infection and ImmunityOngoing
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Study of a newfound immunometabolite in macrophages
The lab of Jan Van den Bossche investigates how metabolism controls macrophages and disease progression.
Amsterdam institute for Infection and ImmunityOngoing
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The ROAB-study: De-implementation strategy to reduce overtreatment of asymptomatic bacteriuria.
Urinary tract infection (UTI) is one of the most common infections for which antimicrobials are prescribed. In the event of asymptomatic bacteriuria (ASB), antimicrobial prescriptions are not always necessary. The aim of this project is to reduce the overtreatment of ASB by using a multifaceted de-implementation strategy.
Amsterdam institute for Infection and ImmunityOngoing
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Towards zero new HIV infections with PROTEST 2.0
Optimal HIV testing strategies are needed to reach zero new HIV infections by 2026.
Amsterdam institute for Infection and ImmunityOngoing
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Training Network for Optimizing Adoptive T cell Therapy of Cancer (T-OP)
The clinical implementation of immunotherapeutics has established T cells as efficient anti-cancer weapons if targeted by specific drugs.
Amsterdam institute for Infection and ImmunityOngoing
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TREAT NL (TREatment of ATopic eczema, The Netherlands) registry
The TREAT NL registry is a national registry of children and adults with moderate-to-severe atopic eczema (AE).
Amsterdam institute for Infection and ImmunityOngoing