Menno Schoonheim: The collapsing brain in MS: Using networks to predict clinical progression
Multiple sclerosis (MS) is a complex neurological disease, where most patients become impaired in motor and cognitive function. In this project I am to understand and predict progression in MS by studying how damage spreads throughout the brain network. I will also implement these latest insights in daily clinical care.
Henne Holstege: Spotlight on the neglected genome to escape dementia
Repetitions in the DNA-code influence the chance of Alzheimer's Disease. To increase our understanding of the heritability of Alzheimer’s Disease, we will compare repetitive sequences in Alzheimer-patients and healthy centenarians. This allows us to use individual genomes to predict who should be treated to prevent AD-associated brain damage, and how.