Amsterdam Cardiovascular Sciences

Hung-Jen (Oliver) Chen

ACS - Atherosclerosis and Aortic Disease AII - Immunology Affiliatie UvA Amsterdam Gastroenterology Endocrinology Metabolism External PhD Candidate, Center for Infection and Molecular Medicine Research Associate, Center for Infection and Molecular Medicine Other Academic Staff, Center of Experimental and Molecular Medicine

Specialization

Molecular Biology

Focus of research

Epigenetic, transcriptomic and metabolomic regulation in macrophages

Latest publications

High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages
Hoepel, W., Chen, H.-J., Geyer, C. E., Allahverdiyeva, S., Manz, X. D., de Taeye, S. W., Aman, J., Mes, L., Steenhuis, M., Griffith, G. R., Bonta, P. I., Brouwer, P. J. M., Caniels, T. G., van der Straten, K., Golebski, K., Jonkers, R. E., Larsen, M. D., Linty, F., Nouta, J. & van Roomen, C. P. A. A. & 16 others, van Baarle, F. E. H. P., van Drunen, C. M., Wolbink, G., Vlaar, A. P. J., de Bree, G. J., Sanders, R. W., Willemsen, L., Neele, A. E., van de Beek, D., Rispens, T., Wuhrer, M., Bogaard, H. J., van Gils, M. J., Vidarsson, G., de Winther, M. & den Dunnen, J., 2 Jun 2021, In: Science translational medicine. 13, 596, eabf8654.
Research output: Contribution to journal › Article* › Academic › peer-review
Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity
Amsterdam UMC Covid-19 Biobank & Amsterdam UMC COVID-19, 26 Feb 2021, In: Science. 371, 6532, abc8378.
Research output: Contribution to journal › Article* › Academic › peer-review
Myeloid Ezh6 Deficiency Limits Atherosclerosis Development
Neele, A. E., Chen, H.-J., Gijbels, M. J. J., van der Velden, S., Hoeksema, M. A., Boshuizen, M. C. S., van den Bossche, J., Tool, A. T., Matlung, H. L., van den Berg, T. K., Lutgens, E. & de Winther, M. P. J., 26 Jan 2021, In: Frontiers in immunology. 11, 594603.
Research output: Contribution to journal › Article* › Academic › peer-review
All publications

Amsterdam Cardiovascular Sciences

Hung-Jen (Oliver) Chen

Specialization

Focus of research

High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

Myeloid Ezh6 Deficiency Limits Atherosclerosis Development