This is associated with injury, wounds, and loss of bone and muscle tissue and strength. On the other hand, sports- and accident-related (traumatic) injuries are increasingly common. This often results in altered structure and mechanical function of musculoskeletal/skin tissues, which need to be repaired or adapted.
Overall Aim
Successful regeneration or adaptation of muscle, tendon, bone, cartilage and skin requires optimal cellular conditions. Those conditions are determined by systemic factors, such as biochemical changes in the circulation that alter the niche of the cells, and by local factors, such as external loads, niche stiffness and architecture, availability of nutrients, oxygen, as well as presence or absence of signalling molecules such as growth factors, cytokines, and steroids.
This program integrates molecular biology, cell physiology, chemistry, biophysics, bioengineering, and medicine across various levels of organization (from cell to organ to whole organism and back) to study structure-function relationships, adaptation and regeneration of musculoskeletal tissues. For innovative solutions in clinical cases there is a need in intensive collaboration between researchers and clinicians. One of the aims of AMS this program is to develop a platform on which researchers, engineers and clinicians work multidisciplinary on clinical issues.
Program Board
- Dr. Nathalie Bravenboer, Amsterdam UMC, location VUmc (Program director);
- Dr. Marco Helder, Amsterdam UMC, location VUmc (Program deputy director);
- Professsor dr. Richard Jaspers, Faculty of Behavioural and Movement Sciences, VU Amsterdam;
Professor dr. Jenneke Klein-Nulend, ACTA;
- Dr. Huub Maas, Faculty of Behavioural and Movement Sciences, VU Amsterdam;
- Dr. Ibrahim Korkmaz ECR, Amsterdam UMC, location VUmc.
Program Members
-
Adriaan LammertsmaPI PROF.DR.
-
Anna van DamPI DR.
-
Dimitra MichaPI DR.
-
Elisabet Farre Guasch
-
Elisabeth EekhoffPI DR.
-
Engelbert SchultenPI PROF.DR.
-
Esther MiddelkoopPI PROF.DR.
-
Frank NiessenPI DR.
-
Hanna C. WillemsPhD
-
Huub Maas
-
Ibrahim Korkmaz
-
Irene van der Horst-BruinsmaPI PROF.DR.
-
J Cheng
-
Jaco SuijkerDRS.
-
Jan de LangeProf. MD DDS PhD
-
Kaj S. EmanuelMSc
-
Kamil OflazogluDRS.
-
Lauria Claeys
-
Lidiia Zhytnik
-
Lisa G. M. van BaarsenPI PhD
-
Maarten VehmeijerDRS.
-
Marco HelderPI DR.
-
Marco RittPROF.DR.
-
Margriet MullenderPI PROF.DR.
-
Marieke J. HenstraMD
-
Marije C. KoeleMD
-
Marjolijn GilijamseDRS.
-
Merle R. Schene
-
Moritz Eggelbusch
-
Nathalie BravenboerPI DR.
-
Paul van ZuijlenPI PROF.DR.
-
Peter Huijing
-
Peter KloenProf. PhD
-
Petrus RaijmakersDR.
-
R.J. Goene
-
Richard GroenDR.
-
Richard Jaspers
-
Rui Yang
-
Stein J. Janssen
-
Tim ForouzanfarPI PROF.DR.
-
Tyler KirbyPhD
-
Wenchao Zhong
-
Willem LemsPI PROF.DR.