The ACS Out of the Box (OOTB) grant aims to stimulate new collaborations between Amsterdam UMC researchers from both locations and strengthen future grant applications. This year, nine projects have been awarded.

The OOTB grant is worth €25,000 and possible options for applications are proof of concept experiments, costs for unique (expensive) imaging or genetics studies, working visit abroad to gain expertise, or any other innovative idea which will improve your future grant application.

This year, the following projects have been awarded:

  • The role of autophagy in healthy and inflamed 3D microvessels (Peter Hordijk/Jeffrey Kroon)
  • Reprogramming foam cells with bioactive lipid mediator (Gijs Kooij/Jan Van den Bossche/Noam Zelcer)
  • Non-coding RNA control of a novel familial arrhythmia syndrome (Reinier Boon/Vincent Christoffels/Harsha Devalla)
  • EMPHOWER: Empagliflozin for Pulmonary Arterial Hypertension Patients with Exclusive Comorbidities (Harm Jan Bogaard/Louis Handoko/Max Nieuwdorp/Erik Duijvelaar)
  • Creating a cell culture model to study the role of resident macrophages on cardiac adaptation to pressure overload (Frances de Man/Menno de Winther)
  • Atrial Fibrillation detection in Lmna mutant mice by an innovative ex vivo precision approach: dissection role of bio-electrical impairment (Bianca Brundel/Bas Boukens)
  • Microbiome-induced expression of regenerating Islet-derived protein 1B to rescue loss of functional beta cells in diabetes and associated cardiovascular complications (Elena Rampanelli/Daniel van Raalte)
  • Unraveling a novel pathomechanism in a novel cardiomyopathy (Josine de Winter/Michel van Weeghel)
  • Peritoneal Dialysis Effluent-derived Extracellular Vesicles (PDE-EVs) to characterize cardiovascular risk in peritoneal dialysis (Lily Jakulj/Marc Vervloet/Michiel Pegtel)

Read more about the procedure of the ACS OOTB call.