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OPTIMIZED AAV-MEDIATED TRANSDUCTION OF CARDIOMYOCYTES
Boink, G. J. J. (Inventor), Jonker, T. (Inventor) & Christoffels, V. M. (Inventor), 20 Nov 2025, IPC No. A61K48/00 C12N15/86, Patent No. WO2025238182A1, 20 Nov 2025, Priority date 15 May 2024Research output: Patent › Academic
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AAV6 vectors provide superior gene transfer compared to AAV9 vectors following intramyocardial administration
Wang, J., Jonker, T., Cervera-Barea, A., Dong, Z., Visser, R. N., Birza, E. E., Boender, A. R., Klerk, M., Yang, Y., Visser, J., Jansen, M. S., Grootswagers, T. C., Bart, C. I., de Jager, S. C. A., Schrödel, S., Thirion, C., Kirzner, O. F., Tan, H. L., de Vries, A. A. F. & Sluijter, J. P. G. & 4 others, , 11 Sept 2025, In: Molecular Therapy - Methods and Clinical Development. 33, 3, 101532.Research output: Contribution to journal › Article › Academic › peer-review
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Directed Evolution of AAV9 for Efficient Gene Expression in Cardiomyocytes In Vitro and In Vivo
Hüttermann, L., Schröder, L. C., Shetty, P. M. V., Jonker, T., Hille, S. S., Kliesow Remes, A., Matzen, A., Grimm, D., Frank, D., Boink, G. J. J., Eschenhagen, T., Schade, D. & Müller, O. J., 1 Feb 2025, In: Human Gene Therapy. 36, 3-4, p. 101-115 15 p.Research output: Contribution to journal › Article › Academic › peer-review
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