The Netherlands Twin Register (NTR) is a national register in which twins, multiples and their parents, siblings, spouses and other family members participate.The research carried out by the NTR focuses on the role of genetic and environmental factors and gene-environment interplay in mental and physical health, lifestyle, personality, and wellbeing.
Nederlands Tweelingen Register logo

Since the early 1980s, the NTR has enrolled around 125,000 twins and a roughly equal number of their relatives. The majority of twin families participate in survey studies, where parents report on their twins, and adult twins and their family members fill in self-report questionnaires. A subset of NTR participants take part in biomaterial collection (e.g., DNA, blood, saliva, stool) and dedicated experimental projects, including e.g. neurocognitive testing, imaging studies, and ambulatory stress measurements. These resources — the longitudinal phenotyping, the extended pedigree structures and the multigeneration genotyping — allow for twin-family research that contributes to gene discovery, causality modeling, and studies of gene-environment interplay.

You can find more information on theNTR website.

APH contact persons: Eco de Geus, Meike Bartels Contact:ntr.fgb@vu.nl