amfAR, The Foundation for AIDS Research, has awarded the Mathilde Krim Fellowship in Basic Biomedical Research to Dr. de Taeye, PhD at Amsterdam UMC. This Fellowship will support an innovative study harnessing the ability of antibodies to home in on cellular targets.

Dr. de Taeye receives $150,000 to support a two-year study using antibody conjugates as a potential cure for HIV. Currently used in the treatment of certain cancers, antibody conjugates bind interventions to antibodies as a means of delivering them to specific cells. In this study, Dr. de Taeye will test several different approaches. The first is a toxin that can be delivered to T cells displaying specific surface signals. Another is an agent to stimulate the internal defenses of HIV-infected cells, leading to a cascade of events that results in destruction by the immune system.

Dr. de Taeye will be mentored by Rogier Sanders, Professor of Virology at Amsterdam UMC, and Marit van Gils, Associate Professor at Amsterdam UMC, who are both former Krim fellows.

amfAR has awarded the Mathilde Krim Fellowship in Basic Biomedical Research since 2008; it is named in honor of amfAR’s late founding chairman Dr. Mathilde Krim. Dr. de Taeye is the 59th Mathilde Krim Fellow. The Mathilde Krim fellowships provide crucial funding for young researchers who often have the most innovative and daring ideas, but for whom securing financial support can be difficult.

Read more on the amfAR website.