Each year, the AGEM research institute organizes a seminar series focused on metabolism: the Tager Lectures. These lectures are named after Professor Joseph Tager, who made important contributions to Fabry, Pompe and Gaucher disease and had a major impact on our understanding of peroxisomal diseases. He was chairman of the Biochemistry Department at the University of Amsterdam (1980-1991).
The Tager Lecture series has been organized since 2017 by a team of AGEM PIs. Right now, Riekelt Houtkooper, Susanne La Fleur, Noam Zelcer and Eveline Bruinstroop are part of the committee. The invited lecturers are researchers from AGEM as well as renowned scholars beyond the Amsterdam UMC. They are all known for their valuable work in the field of gastroenterology, endocrinology and metabolism. An overview of the speakers can be found below. See the events page to know when the next Tager Lecture is planned.
2024
Tuesday January 9: Prof. dr. Nicolaas Deutz
Health & Kinesiology, Texas A&M University
"Stable isotope methods in human clinical research"
Thursday March 7: Dr. Sean Froese
Head of Research, Division of Metabolism, University Children’s Hospital, Zurich
"Inborn disorders of folateand vitamin B12 metabolism: causes, consequences and the push for novel treatments"
2023
Thursday February 2: Dr. Lena Pernas
Max Planck Institute for Biology of Ageing
"Organelle and metabolic dynamics of infection"
Thursday April 6: Prof. dr. Duncan Basset
Molecular Endocrinology Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College London
“Advances in understanding the skeletal consequences of thyroid disease”
Lena Pernas
Duncan Bassett
Joerg Heeren
Ron Heeren
Thursday June 8: Prof. dr. Joerg Heeren
University Medical Center Hamburg-Eppendorf, Department for Biochemistry and Molecular Cell Biology
“Brown adipose tissue and lipid metabolism”
Thursday July 20: Prof. dr. Ron Heeren
The Maastricht MultiModal Molecular Imaging institute, Maastricht University
“Seeing is believing: visualizing cellular metabolism with imaging mass spectrometry”
Jaap Keijer
Felix Hartmann
Thursday September 7: Prof. dr. Jaap Keijer
Human and Animal Physiology, Wageningen University
“Functional and pathway changes in the human aging muscle”
Thursday November 9: Dr. Felix Hartmann
German Cancer Research Center (DKFZ), Heidelberg
“Quantifying metabolic regulation in tissue microenvironments via multiplexed imaging”
2022
Thursday October 13: Dr. Sabine Fuchs
Department of Metabolic Diseases, UMC Utrecht
"Prime Time": Adult stem cell (organoid) technology and precise gene (prime) editing to develop innovative therapies for patients with metabolic diseases.
Hans-Georg Sprenger
Sabine Fuchs
2021
Thursday October 28: Dr. Hans-Georg Sprenger
Whitehead Institute for Biomedical Research & Massachusetts Institute of Technology, Cambridge, USA.
"Mitochondrial Proteostasis and Inflammation”
2020
Thursday January 30: Prof. dr. Anu Suomalainen
Research Program of Stem Cells and MetabolismFaculty of Medicine, Biomedicum Helsinki, University of Helsinki, Finland.
“Metabolic mechanisms of tissue specificity: lessons from mitochondrial disorders”
Anu Suomalainen
Stephan Herzig
Xavier Fioramonti
Thursday October 29: Prof. dr. Stephan Herzig
Helmholtz Diabetes Center, Institute for Diabetes and Cancer, Munich, Germany.
“Coordination of systemic metabolism by inter-cellular signaling”
Thursday December 10: PhD, Associate Prof. Xavier Fioramonti
INRAE, NutriNeuro Institute, Bordeaux, France.
“Brain glucose- and insulin-sensing in physiological and diabetic conditions
2019
Thursday May 9: Prof. Dr. Paul Dawson
Division of Pediatric Gastroenterology, Hepatology & Nutrition, Emory University School of Medicine, Atlanta, Georgia, USA.
“Molecular Mechanisms of Intestinal Bile Acid Transport and Signaling”
Thursday September 12: Prof. Dr. Christian Wolfrum
Department of Health Science and Technology, Federal Institute of Technology (ETH Zurich), Zurich, Switzerland.
“Brown fat composition and function regulating systemic metabolism”
Paul Dawson
Christian Wolfrum
Katrien de Bock
Jan van den Bossche
Thursday October 31: Dr. Katrien de Bock
Department of Health Science and Technology, Federal Institute of Technology (ETH Zurich), Zurich, Switzerland.
“Metabolic crosstalk between the endothelium and macrophages during recovery from hindlimb ischemia”
Thursday December 12: Dr. Jan Van den Bossche
Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
“Metabolic control of macrophage activation”
2018
Monday February 5: Dr. Celine Riera
Diabetes and Obesity Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, USA.
"Chemosensory neurons in the control of metabolic homeostasis"
Thursday March 8: Dr. Clara van Karnebeek
Departments of Pediatrics & Clinical Genetics, Amsterdam UMC, Amsterdam, The Netherlands.
“Translating -omics data into diagnosis and treatment for neurometabolic diseases”
Thursday May 24: Dr. Thomas Langer
Max-Planck-Institute for Biology of Ageing, Cologne, Germany.
“Proteolytic control of mitochondrial proteostasis”
Thursday September 13: Dr. Ruben Nogueiras
University of Santiago de Compostela, Santiago de Compostela, Spain.
"Unraveling the metabolic role of p53”
Thursday December 6: Dr. Sophie Steculorum
Max Planck Institute for Metabolism Research, Köln, Germany
“Central control of feeding and systemic insulin sensitivity”