Amsterdam Gastroenterology Endocrinology Metabolism

Clinical, diagnostic and genetic aspects of central congenital hypothyroidism (CH) The Dutch neonatal screening program allows for the detection of congenital central hypothyroidism (CCeH) and facilitated identification of patients with CCeH over the past decades.

Targeting hepatic bile salt uptake to treat cholestasis or the metabolic syndrome In this project we aim to understand the role of bile acids (and its dynamics) in energy, fat and glucose homeostasis, and in inflammation.

Gluten-related Neurological Disorders Various neurodegenerative disorders have been associated with an inappropriate reaction to dietary gluten intake. The underlying neuropathological mechanism is still unclear.