Research institutes

Cancer Center Amsterdam

Marc van de Vijver

PROF.DR.

Affiliatie UvA Affiliatie VU CCA - Cancer biology and immunology Full Professor, CCA - Cancer biology and immunology CCA - Imaging and biomarkers Full Professor, CCA - Imaging and biomarkers Full Professor, Pathology

Specialization

Pathology

Focus of research

Genetic alterations and gene expression profiles of solid tumors

Key publications
Latest publications

Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Nik-Zainal, S., Davies, H., Staaf, J., Ramakrishna, M., Glodzik, D., Zou, X., Martincorena, I., Alexandrov, L. B., Martin, S., Wedge, D. C., van Loo, P., Ju, Y. S., Smid, M., Brinkman, A. B., Morganella, S., Aure, M. R., Lingjærde, O. C., Langerød, A., Ringnér, M. & Ahn, S.-M. & 68 others, Boyault, S., Brock, J. E., Broeks, A., Butler, A., Desmedt, C., Dirix, L., Dronov, S., Fatima, A., Foekens, J. A., Gerstung, M., Hooijer, G. K. J., Jang, S. J., Jones, D. R., Kim, H.-Y., King, T. A., Krishnamurthy, S., Lee, H. J., Lee, J.-Y., Li, Y., McLaren, S., Menzies, A., Mustonen, V., O'Meara, S., Pauporté, I., Pivot, X., Purdie, C. A., Raine, K., Ramakrishnan, K., Rodríguez-González, F. G., Romieu, G., Sieuwerts, A. M., Simpson, P. T., Shepherd, R., Stebbings, L., Stefansson, O. A., Teague, J., Tommasi, S., Treilleux, I., van den Eynden, G. G., Vermeulen, P., Vincent-Salomon, A., Yates, L., Caldas, C., van't Veer, L., Tutt, A., Knappskog, S., Tan, B. K. T., Jonkers, J., Borg, Å., Ueno, N. T., Sotiriou, C., Viari, A., Futreal, P. A., Campbell, P. J., Span, P. N., van Laere, S., Lakhani, S. R., Eyfjord, J. E., Thompson, A. M., Birney, E., Stunnenberg, H. G., van de Vijver, M. J., Martens, J. W. M., Børresen-Dale, A.-L., Richardson, A. L., Kong, G., Thomas, G. & Stratton, M. R., 2016, In: Nature. 534, 7605, p. 47-+
Research output: Contribution to Journal › Article › Academic › peer-review
Search for a gene expression signature of breast cancer local recurrence in young women
Servant, N., Bollet, M. A., Halfwerk, H., Bleakley, K., Kreike, B., Jacob, L., Sie, D., Kerkhoven, R. M., Hupé, P., Hadhri, R., Fourquet, A., Bartelink, H., Barillot, E., Sigal-Zafrani, B. & van de Vijver, M. J., 15 Mar 2012, In: Clinical Cancer Research. 18, 6, p. 1704-15 12 p.
Research output: Contribution to Journal › Article › Academic › peer-review
Retrospective analysis of metastatic behaviour of breast cancer subtypes
Savci-Heijink, C. D., Halfwerk, H., Hooijer, G. K. J., Horlings, H. M., Wesseling, J. & van de Vijver, M. J., 2015, In: Breast Cancer Research and Treatment. 150, 3, p. 547-557
Research output: Contribution to Journal › Article › Academic › peer-review
All publications

Temporal and spatial composition of the tumor microenvironment predicts response to immune checkpoint inhibition in metastatic TNBC
Greenwald, N. F., Nederlof, I., Sowers, C., Ding, D. Y., Park, S., Kong, A., Houlahan, K. E., Varra, S. R., de Graaf, M., Geurts, V., Liu, C. C., Ranek, J. S., Voorwerk, L., de Maaker, M., Kagel, A., McCaffrey, E., Khan, A., Yeh, C. Y., Fullaway, C. C. & Khair, Z. & 18 others, Simon, B. G., Bai, Y., Piyadasa, H., Risom, T., Delmastro, A., Hartmann, F. J., Mangiante, L., Sotomayor-Vivas, C., Bendall, S. C., Schumacher, T. N., Ma, Z., Bosse, M., van de Vijver, M. J., Tibshirani, R., Horlings, H. M., Curtis, C., Kok, M. & Angelo, M., 1 Mar 2026, In: Nature Cancer. 7, 3, p. 435-450 16 p.
Research output: Contribution to Journal › Article › Academic › peer-review
Performance Assessment of a Deep Learning–based Algorithm for Ovarian Cancer Histotyping in an Independent Data Set
Zelisse, H. S., Asadi-Aghbolaghi, M., Farahani, H., Snijders, M. L. H., Hooijer, G. K. J., Mom, C. H., van Gent, M. D. J. M., Dijk, F., Horlings, H. M., van de Vijver, M. J. & Bashashati, A., Feb 2026, In: American journal of surgical pathology. 50, 2, p. 179-188 10 p.
Research output: Contribution to Journal › Article › Academic › peer-review
Improving cell-free DNA detection in advanced-stage high-grade serous ovarian cancer using combined TP53 mutational status and copy number changes
Zelisse, H. S., van der Pol, Y., Mouliere, F., Dijk, F., Halfwerk, J. B. G., Mearadji, B., Beenen, L. F. M., Reinten, R. J., Cillessen, S. A. G. M., Hooijer, G. K. J., Snijders, M. L. H., van de Vijver, M. J., van Gent, M. D. J. M. & Mom, C. H., 1 Aug 2025, In: Pathology, Research and Practice. 272, p. 156038 1 p.
Research output: Contribution to Journal › Article › Academic › peer-review
All publications

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Cancer Center Amsterdam

Cancer Center Amsterdam

Marc van de Vijver

Specialization

Focus of research

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

Search for a gene expression signature of breast cancer local recurrence in young women

Retrospective analysis of metastatic behaviour of breast cancer subtypes

Temporal and spatial composition of the tumor microenvironment predicts response to immune checkpoint inhibition in metastatic TNBC

Performance Assessment of a Deep Learning–based Algorithm for Ovarian Cancer Histotyping in an Independent Data Set

Improving cell-free DNA detection in advanced-stage high-grade serous ovarian cancer using combined TP53 mutational status and copy number changes