General
On Wednesday May 6th, the Tager seminar series will continue with a new lecture by Dr. Benedetta Artegiani and Dr. Delilah Hendriks, who work as Principal Investigators at the Princess Maxima Center in Utrecht, Netherlands.
Human liver organoids for disease modeling and beyond
In recent years, human organoids have emerged as indispensable models for biomedical research. In this seminar, we will present the recent efforts of our lab in establishing human liver organoid models that can capture some of the functionality and the complexity of human organ. We will discuss how we exploit these for disease models, with a focus on metabolic diseases and how these can contribute to mechanisms of cancer initiation. We will also focus on the technological advances, such as complex genetic engineering and generation of assembloids, that allow us to use these models to answer biological questions.