Organization

  • Study Indicates Type 2 Diabetes Operates Differently Across Weight Profiles
    Study Indicates Type 2 Diabetes Operates Differently Across Weight Profiles Research published today in Diabetologia by Amsterdam UMC and the University of Ghana reveals that type 2 diabetes manifests in two fundamentally different ways depending on a patient's body mass index (BMI). While type 2 diabetes in patients with a higher BMI is primarily driven by insulin resistance, the study demonstrates that in individuals within a lower BMI range, the condition is caused by the pancreas failing to produce sufficient insulin. Despite these opposing biological mechanisms, medical professionals currently treat both groups with the exact same medications.
  • World First: First Phase 3 Trial of In Vivo CRISPR Therapy Successfully Completed - CRISPR treatment comes one step closer to reality
    World First: First Phase 3 Trial of In Vivo CRISPR Therapy Successfully Completed - CRISPR treatment comes one step closer to reality Researchers from Amsterdam UMC, in collaboration with other hospitals, have successfully completed the first-ever Phase 3 study of an in vivo CRISPR therapy. In this large-scale, double-blind Phase 3 trial, 80 patients with hereditary angioedema were randomized to receive either the CRISPR therapy or a placebo. CRISPR therapy is a medical technique that allows doctors to precisely modify errors in cellular DNA to treat specific hereditary diseases. Danny Cohn, leader of the research, is highly enthusiastic: "The study demonstrates that the therapy is genuinely effective and safe. This confirmation is exactly what regulatory authorities need to approve the very first in vivo CRISPR gene editing treatment for the market."
  • Amsterdam UMC gives future generations a seat in Parliament
    Amsterdam UMC gives future generations a seat in Parliament "We must create policy and take action today as if the lives of future generations depend on it. Because they do," says Tessa Roseboom. As the Future Generations Commissioner at Amsterdam UMC, her mission is to make those lives and the interests of future generations audible, visible, and tangible. Today, she symbolically grants them a seat in the House of Representatives’ Committee on Health, Welfare and Sport (VWS) by giving each member a chair and a powerful manifesto.

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